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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
21/01/2020 |
Actualizado : |
21/01/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D. |
Afiliación : |
LOUISIANE DE CARVALHO NUNES, Department of Veterinary Science, Federal University of Espírito Santo, Alegre, Espírito Santo, Brazil; BRYAN L. STEGELMEIER, USDA-ARS Poisonous Plant Research Laboratory, USA; DANIEL COOK, USDA-ARS Poisonous Plant Research Laboratory, USA; JAMES A. PFISTER, USDA-ARS Poisonous Plant Research Laboratory, USA; DALE R. GARDNER, USDA-ARS Poisonous Plant Research Laboratory, USA; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Veterinary Hospital, Center for Health and Rural Technology, Patos Campus, Federal University of Campina Grande, Brazil; KEVIN D. WELCH, USDA-ARS Poisonous Plant Research Laboratory, USA. |
Título : |
Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016 |
ISSN : |
0041-0101 |
DOI : |
10.1016/j.toxicon.2019.09.016 |
Idioma : |
Inglés |
Notas : |
Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019. |
Contenido : |
ABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine.
© 2019 MenosABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic a... Presentar Todo |
Palabras claves : |
Astragalus; Calystegines; Ipomoea; Locoweed; PLATAFORMA SALUD ANIMAL; Swainsonine. |
Asunto categoría : |
A50 Investigación agraria |
Marc : |
LEADER 02878naa a2200301 a 4500 001 1060655 005 2020-01-21 008 2019 bl uuuu u00u1 u #d 022 $a0041-0101 024 7 $a10.1016/j.toxicon.2019.09.016$2DOI 100 1 $aDE CARVALHO NUNES, L. 245 $aClinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats.$h[electronic resource] 260 $c2019 500 $aArticle history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019. 520 $aABSTRACT. The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine. © 2019 653 $aAstragalus 653 $aCalystegines 653 $aIpomoea 653 $aLocoweed 653 $aPLATAFORMA SALUD ANIMAL 653 $aSwainsonine 700 1 $aSTEGELMEIER, B. L. 700 1 $aCOOK, D. 700 1 $aPFISTER, J. A. 700 1 $aGARDNER, D. R. 700 1 $aRIET-CORREA, F. 700 1 $aWEICH, K. D. 773 $tToxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016
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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha actual : |
21/02/2014 |
Actualizado : |
11/05/2022 |
Tipo de producción científica : |
Documentos |
Autor : |
PEREYRA, S.; FASSIO, A.; STEWART, S.; RODRIGUEZ, M.; VILARÓ, D. |
Afiliación : |
SILVIA ANTONIA PEREYRA CORREA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ALBERTO SANTIAGO FASSIO ARAUJO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SILVINA MARIA STEWART SONEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARCELO JULIAN RODRIGUEZ ALONZO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO CARLOS VILARO NIETO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Estrategias para el manejo de Phomopsis en girasol. |
Fecha de publicación : |
2008 |
Fuente / Imprenta : |
In: Jornada INIA La Estanzuela: cultivos de verano. Young, Río Negro: INIA La Estanzuela, Sociedad Rural de Río Negro, agosto 2008. |
Páginas : |
p.4-9. |
Serie : |
(INIA Serie Actividades de Difusión ; 550). |
Idioma : |
Español |
Contenido : |
La Phomopsis (cancro de tallo y/o capítulo) del girasol es causada por Diaporthe helianthi (estado asexual: Phomopsis helianthi). Esta enfermedad, que fue detectada por primera vez en el país en la zafra 2002/2003 (3),produce pérdidas de rendimiento de grano.
Durante la estación de crecimiento del girasol, no se producen ciclos secundarios de la enfermedad, por lo que la cantidad de inóculo primario (ascosporas producidas en el rastrojo), la sucesión de descargas desde el rastrojo y las condiciones predisponentes para la infección son fundamentales en el desarrollo de la epidemia. Para establecer estrategias efectivas de manejo para Phomopsis, es necesario tener
conocimientos de cómo las variables climáticas afectan la infección y el desarrollo de la enfermedad en función a su vez de la fenología del cultivo, del comportamiento de los cultivares disponibles frente a Phomopsis, y de la efectividad del control químico. |
Palabras claves : |
PHOMOPSIS HELIANTHI. |
Thesagro : |
FITOPATOLOGÍA; GIRASOL; HELIANTHUS ANNUS. |
Asunto categoría : |
H20 Enfermedades de las plantas |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16427/1/ad-550.pdf;verano#page=7
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Marc : |
LEADER 01696naa a2200241 a 4500 001 1040233 005 2022-05-11 008 2008 bl uuuu u00u1 u #d 100 1 $aPEREYRA, S. 245 $aEstrategias para el manejo de Phomopsis en girasol.$h[electronic resource] 260 $c2008 300 $ap.4-9. 490 $a(INIA Serie Actividades de Difusión ; 550). 520 $aLa Phomopsis (cancro de tallo y/o capítulo) del girasol es causada por Diaporthe helianthi (estado asexual: Phomopsis helianthi). Esta enfermedad, que fue detectada por primera vez en el país en la zafra 2002/2003 (3),produce pérdidas de rendimiento de grano. Durante la estación de crecimiento del girasol, no se producen ciclos secundarios de la enfermedad, por lo que la cantidad de inóculo primario (ascosporas producidas en el rastrojo), la sucesión de descargas desde el rastrojo y las condiciones predisponentes para la infección son fundamentales en el desarrollo de la epidemia. Para establecer estrategias efectivas de manejo para Phomopsis, es necesario tener conocimientos de cómo las variables climáticas afectan la infección y el desarrollo de la enfermedad en función a su vez de la fenología del cultivo, del comportamiento de los cultivares disponibles frente a Phomopsis, y de la efectividad del control químico. 650 $aFITOPATOLOGÍA 650 $aGIRASOL 650 $aHELIANTHUS ANNUS 653 $aPHOMOPSIS HELIANTHI 700 1 $aFASSIO, A. 700 1 $aSTEWART, S. 700 1 $aRODRIGUEZ, M. 700 1 $aVILARÓ, D. 773 $tIn: Jornada INIA La Estanzuela: cultivos de verano. Young, Río Negro: INIA La Estanzuela, Sociedad Rural de Río Negro, agosto 2008.
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